The small GTP-binding protein Rho links G protein-coupled receptors and Gα(12 )to the serum response element and to cellular transformation

Receptors coupled to heterotrimeric G proteins can effectively stimulate growth promoting pathways in a large variety of cell types, and if persistently activated, these receptors can also behave as dominant-acting oncoproteins. Consistently, activating mutations for G proteins of the Gα(s) and Gα(i...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Fromm, Christian, Coso, Omar A., Montaner, Silvia, Xu, Ningzhi, Gutkind, J. Silvio
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.19.10098
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