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The small GTP-binding protein Rho links G protein-coupled receptors and Gα(12 )to the serum response element and to cellular transformation
Receptors coupled to heterotrimeric G proteins can effectively stimulate growth promoting pathways in a large variety of cell types, and if persistently activated, these receptors can also behave as dominant-acting oncoproteins. Consistently, activating mutations for G proteins of the Gα(s) and Gα(i...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1997
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23316/ https://ncbi.nlm.nih.gov/pubmed/9294169 |
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