The Emerging Mutational Landscape of G-proteins and G-protein Coupled Receptors in Cancer

Aberrant expression and activity of G proteins and G protein coupled receptors (GPCRs) are frequently associated with tumorigenesis. Deep sequencing studies show that 4.2% of tumors carry activating mutations in GNAS (encoding Gα(s)), and that oncogenic activating mutants in genes encoding Gα(q) fam...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: O’Hayre, Morgan, Vázquez-Prado, José, Kufareva, Irina, Stawiski, Eric W., Handel, Tracy M., Seshagiri, Somasekar, Gutkind, J. Silvio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068741/
https://ncbi.nlm.nih.gov/pubmed/23640210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3521
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