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Molecular Mechanisms Deployed by Virally Encoded G Protein Coupled Receptors in Human Diseases

G-protein coupled receptors (GPCRs) represent the largest family of cell surface molecules involved in signal transduction. Surprisingly, open reading frames for multiple GPCRs were hijacked in the process of co-evolution between herpesviridae family viruses and their human and mammalian hosts. Vira...

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Hlavní autoři: Montaner, Silvia, Kufareva, Irina, Abagyan, Ruben, Gutkind, J. Silvio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074518/
https://ncbi.nlm.nih.gov/pubmed/23092247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010510-100608
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