N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus

The native, functional HIV-1 envelope glycoprotein (Env) complex is a trimer of two non-covalently associated subunits: the gp120 surface glycoprotein and the gp41 transmembrane glycoprotein. However, various non-functional forms of Env are present on virus particles and HIV-1-infected cells, some o...

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Autores principales: Dey, Antu K., David, Kathryn B., Ray, Neelanjana, Ketas, Thomas J., Klasse, Per J., Doms, Robert W., Moore, John P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2317825/
https://ncbi.nlm.nih.gov/pubmed/18031785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.10.018
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