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Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1

The HIV-1 envelope glycoprotein is expressed on the viral membrane as a trimeric complex, formed by three gp120 surface glycoproteins non-covalently associated with three membrane-anchored gp41 subunits. The labile nature of the association between gp120 and gp41 hinders the expression of soluble, f...

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書誌詳細
主要な著者: Dey, Antu K., David, Kathryn B., Klasse, Per J., Moore, John P.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857345/
https://ncbi.nlm.nih.gov/pubmed/17092531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.09.046
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