Role of Hydrophobic Residues in the Central Ectodomain of gp41 in Maintaining the Association between Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Subunits gp120 and gp41

The interaction between the gp120 and gp41 subunits of the human immunodeficiency virus envelope glycoprotein serves to stabilize the virion form of the complex and to transmit receptor-induced conformational changes in gp120 to trigger the membrane fusion activity of gp41. In this study, we used si...

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Bibliographic Details
Published in:J Virol
Main Authors: York, Joanne, Nunberg, Jack H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387687/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078976/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.9.4921-4926.2004
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