Loading...
Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits
The ATP-sensitive potassium channel (K-ATP channel) plays a key role in insulin secretion from pancreatic β-cells. It is closed by glucose metabolism, which stimulates secretion, and opened by the drug diazoxide, which inhibits insulin release. Metabolic regulation is mediated by changes in ATP and...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences of the USA
1997
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23175/ https://ncbi.nlm.nih.gov/pubmed/9238070 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|