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Mechanism of ATP-sensitive K Channel Inhibition by Sulfhydryl Modification

ATP-sensitive potassium (K(ATP)) channels are reversibly inhibited by intracellular ATP. Agents that interact with sulfhydryl moieties produce an irreversible inhibition of K(ATP) channel activity when applied to the intracellular membrane surface. ATP appears to protect against this effect, suggest...

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Bibliografische gegevens
Hoofdauteurs: Trapp, Stefan, Tucker, Stephen J., Ashcroft, Frances M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 1998
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229416/
https://ncbi.nlm.nih.gov/pubmed/9725892
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