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The role of lysine 185 in the Kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP
1. ATP-sensitive potassium (K(ATP)) channels are composed of pore-forming Kir6.2 and regulatory SUR subunits. A truncated isoform of Kir6.2, Kir6.2ΔC26, forms ATP-sensitive channels in the absence of SUR1, suggesting the ATP-inhibitory site lies on Kir6.2. 2. Previous studies have shown that mutatio...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269625/ https://ncbi.nlm.nih.gov/pubmed/10545134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00661.x |
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