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Phentolamine block of K(ATP) channels is mediated by Kir6.2
The ATP-sensitive K(+)-channel (K(ATP) channel) plays a key role in insulin secretion from pancreatic β cells. It is closed both by glucose metabolism and the sulfonylurea drugs that are used in the treatment of noninsulin-dependent diabetes mellitus, thereby initiating a membrane depolarization tha...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The National Academy of Sciences of the USA
1997
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23609/ https://ncbi.nlm.nih.gov/pubmed/9326676 |
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