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Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits

The ATP-sensitive potassium channel (K-ATP channel) plays a key role in insulin secretion from pancreatic β-cells. It is closed by glucose metabolism, which stimulates secretion, and opened by the drug diazoxide, which inhibits insulin release. Metabolic regulation is mediated by changes in ATP and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Trapp, Stefan, Tucker, Stephen J., Ashcroft, Frances M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences of the USA 1997
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC23175/
https://ncbi.nlm.nih.gov/pubmed/9238070
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