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Pyridine nucleotide regulation of the K(ATP) channel Kir6.2/SUR1 expressed in Xenopus oocytes

The pancreatic β-cell type of ATP-sensitive potassium (K(ATP)) channel (Kir6.2/SUR1) is inhibited by intracellular ATP and ADP, which bind to the Kir6.2 subunit, and is activated by Mg-nucleotide interaction with the regulatory sulphonylurea receptor subunits (SUR1). The nicotinamide adenine dinucle...

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Detalhes bibliográficos
Main Authors: Dabrowski, Michael, Trapp, Stefan, Ashcroft, Frances M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343050/
https://ncbi.nlm.nih.gov/pubmed/12766240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.041715
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