Galectin-3 Reduces the Severity of Pneumococcal Pneumonia by Augmenting Neutrophil Function

The Gram-positive Streptococcus pneumoniae is the leading cause of community-acquired pneumonia worldwide, resulting in high mortality. Our in vivo studies show that galectin-3(−/−) mice develop more severe pneumonia after infection with S. pneumoniae, as demonstrated by increased bacteremia and lun...

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Detalhes bibliográficos
Main Authors: Farnworth, Sarah L., Henderson, Neil C., MacKinnon, Alison C., Atkinson, Kirsten M., Wilkinson, Tom, Dhaliwal, Kevin, Hayashi, Katsutoshi, Simpson, A. John, Rossi, Adriano G., Haslett, Christopher, Sethi, Tariq
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312371/
https://ncbi.nlm.nih.gov/pubmed/18202191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070870
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