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Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice

Atherosclerosis is a major risk factor for cardiovascular disease (CVD) and stroke. Galectin-3 is a carbohydrate-binding lectin implicated in the pathophysiology of CVD and is highly expressed within atherosclerotic lesions in mice and humans. The object of this present study was to use genetic dele...

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Hlavní autoři: MacKinnon, Alison C, Liu, Xiaojun, Hadoke, Patrick WF, Miller, Mark R, Newby, David E, Sethi, Tariq
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641797/
https://ncbi.nlm.nih.gov/pubmed/23426722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwt006
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