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Galectin-3 Expression and Secretion Links Macrophages to the Promotion of Renal Fibrosis
Macrophages have been proposed as a key cell type in the pathogenesis of renal fibrosis; however, the mechanism by which macrophages drive fibrosis is still unclear. We show that expression of galectin-3, a β-galactoside-binding lectin, is up-regulated in a mouse model of progressive renal fibrosis...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2312353/ https://ncbi.nlm.nih.gov/pubmed/18202187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070726 |
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