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Galectin-3 regulates myofibroblast activation and hepatic fibrosis

Central to fibrogenesis and the scarring of organs is the activation of fibroblasts into matrix-secreting myofibroblasts. We demonstrate that Galectin-3 expression is up-regulated in established human fibrotic liver disease and is temporally and spatially related to the induction and resolution of e...

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Hlavní autoři: Henderson, Neil C., Mackinnon, Alison C., Farnworth, Sarah L., Poirier, Francoise, Russo, Francesco P., Iredale, John P., Haslett, Christopher, Simpson, Kenneth J., Sethi, Tariq
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458794/
https://ncbi.nlm.nih.gov/pubmed/16549783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511167103
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