Laddar...
Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity.
Small-molecule inhibitors of the housekeeping enzyme farnesyltransferase (FT) suppress the malignant growth of Ras-transformed cells. Previous work suggested that the activity of these compounds reflected effects on actin stress fiber regulation rather than Ras inhibition. Rho proteins regulate stre...
Sparad:
| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1995
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC230914/ https://ncbi.nlm.nih.gov/pubmed/8524226 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|