A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A.

Cyclic AMP (cAMP) stimulates the expression of numerous genes through the protein kinase A (PK-A)-mediated phosphorylation of the nuclear factor CREB at Ser-133 (G. A. Gonzalez and M. R. Montminy, Cell 59:675-680, 1989). Like other signal transduction pathways, cAMP induces gene expression with burs...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Armstrong, R, Wen, W, Meinkoth, J, Taylor, S, Montminy, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230407/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1826
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