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Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation.

We have shown that the transcriptional activity of the protooncogene jun (c-jun) promoter is repressed by a transcription factor, the cAMP response element-binding protein (CREB). This repression can be alleviated when CREB is phosphorylated by the catalytic subunit of protein kinase A. Repression c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lamph, W W, Dwarki, V J, Ofir, R, Montminy, M, Verma, I M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1990
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC54101/
https://ncbi.nlm.nih.gov/pubmed/2140898
Tagiau: Ychwanegu Tag
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