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A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A.

Cyclic AMP (cAMP) stimulates the expression of numerous genes through the protein kinase A (PK-A)-mediated phosphorylation of the nuclear factor CREB at Ser-133 (G. A. Gonzalez and M. R. Montminy, Cell 59:675-680, 1989). Like other signal transduction pathways, cAMP induces gene expression with burs...

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Pubblicato in:Mol Cell Biol
Autori principali: Armstrong, R, Wen, W, Meinkoth, J, Taylor, S, Montminy, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230407/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862172/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1826
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