Loading...

The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells.

Many eukaryotic genes are regulated by cAMP through a conserved cAMP response element (CRE). Here we show that, in the pancreatic islet cell line Tu6, a well-characterized CRE in the somatostatin gene does not provide cAMP responsiveness but functions as an essential element for its basal activity....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Leonard, J, Serup, P, Gonzalez, G, Edlund, T, Montminy, M
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49477/
https://ncbi.nlm.nih.gov/pubmed/1352885
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!