Resistance of Human Cytomegalovirus to the Benzimidazole l-Ribonucleoside Maribavir Maps to UL27

1-(β-d-Ribofuranosyl)-2,5,6-trichlorobenzimidazole (TCRB) and its 2-bromo analog, BDCRB, are potent and selective inhibitors of human cytomegalovirus (HCMV) DNA processing and packaging. Since they are readily metabolized in vivo, analogs were synthesized to improve biostability. One of these, 1-(β-...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Virol
Päätekijät:	Komazin, Gloria, Ptak, Roger G., Emmer, Brian T., Townsend, Leroy B., Drach, John C.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2003
Aiheet:	Vaccines and Antiviral Agents
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229258/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11499-11506.2003
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!