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Resistance of Human Cytomegalovirus to the Benzimidazole l-Ribonucleoside Maribavir Maps to UL27

1-(β-d-Ribofuranosyl)-2,5,6-trichlorobenzimidazole (TCRB) and its 2-bromo analog, BDCRB, are potent and selective inhibitors of human cytomegalovirus (HCMV) DNA processing and packaging. Since they are readily metabolized in vivo, analogs were synthesized to improve biostability. One of these, 1-(β-...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Komazin, Gloria, Ptak, Roger G., Emmer, Brian T., Townsend, Leroy B., Drach, John C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229258/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557635/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11499-11506.2003
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