Resistance of Human Cytomegalovirus to the Benzimidazole l-Ribonucleoside Maribavir Maps to UL27

1-(β-d-Ribofuranosyl)-2,5,6-trichlorobenzimidazole (TCRB) and its 2-bromo analog, BDCRB, are potent and selective inhibitors of human cytomegalovirus (HCMV) DNA processing and packaging. Since they are readily metabolized in vivo, analogs were synthesized to improve biostability. One of these, 1-(β-...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Komazin, Gloria, Ptak, Roger G., Emmer, Brian T., Townsend, Leroy B., Drach, John C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC229258/
https://ncbi.nlm.nih.gov/pubmed/14557635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11499-11506.2003
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk