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Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells
The inhibitor of apoptosis (IAP) protein Survivin is expressed in most cancers and is a key factor in maintaining apoptosis resistance. Although several IAPs have been shown to act as direct inhibitors of caspases, the precise antiapoptotic function of Survivin remains controversial. To clarify the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292403/ https://ncbi.nlm.nih.gov/pubmed/14712209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1206978 |
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