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Caspases 3 and 7: Key Mediators of Mitochondrial Events of Apoptosis
The current model of apoptosis holds that upstream signals lead to activation of downstream effector caspases. We generated mice deficient in the two effectors, caspase 3 and caspase 7, which died immediately after birth with defects in cardiac development. Fibroblasts lacking both enzymes were high...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738210/ https://ncbi.nlm.nih.gov/pubmed/16469926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1115035 |
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