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In Vitro and In Vivo Protection of Stellate Cells from Apoptosis by Leptin
Hepatic fibrogenesis is reduced in the absence of leptin. We hypothesized that leptin protects hepatic stellate cells (HSCs) from apoptosis and tested this in in vitro and in vivo systems. (i) Fas ligand (fas-L)-mediated apoptosis was induced in vitro in activated HSCs in the absence and presence of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219756/ https://ncbi.nlm.nih.gov/pubmed/16957995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-006-9244-8 |
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