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Induction of melanoma cell apoptosis and inhibition of tumor growth using a cell-permeable Survivin antagonist

The inhibitor of apoptosis gene family member Survivin is highly expressed in most tumors, and appears to be a promising target for cancer therapy. Although a variety of Survivin antagonists have been shown to induce apoptosis in malignant cells, the potential utility of these agents is limited by i...

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Bibliografiske detaljer
Main Authors: Yan, H, Thomas, J, Liu, T, Raj, D, London, N, Tandeski, T, Leachman, SA, Lee, RM, Grossman, D
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292411/
https://ncbi.nlm.nih.gov/pubmed/16702945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209676
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