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Inhibition of melanoma tumor growth in vivo by survivin targeting

A role of apoptosis (programmed cell death) in tumor formation and growth was investigated by targeting the apoptosis inhibitor survivin in vivo. Expression of a phosphorylation-defective survivin mutant (Thr(34)→Ala) triggered apoptosis in several human melanoma cell lines and enhanced cell death i...

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書誌詳細
主要な著者: Grossman, Douglas, Kim, Paul J., Schechner, Jeffrey S., Altieri, Dario C.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC14640/
https://ncbi.nlm.nih.gov/pubmed/11149963
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