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Inhibition of melanoma tumor growth in vivo by survivin targeting
A role of apoptosis (programmed cell death) in tumor formation and growth was investigated by targeting the apoptosis inhibitor survivin in vivo. Expression of a phosphorylation-defective survivin mutant (Thr(34)→Ala) triggered apoptosis in several human melanoma cell lines and enhanced cell death i...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC14640/ https://ncbi.nlm.nih.gov/pubmed/11149963 |
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