Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation

The transcriptional coactivator PGC-1α is a potent regulator of several metabolic pathways, including, in particular, the activation of oxidative phosphorylation and mitochondrial biogenesis. Recent evidence suggests that increasing PGC-1α activity may have beneficial effects in various conditions,...

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Detalles Bibliográficos
Autores principales: Arany, Zoltan, Wagner, Bridget K., Ma, Yanhong, Chinsomboon, Jessica, Laznik, Dina, Spiegelman, Bruce M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290788/
https://ncbi.nlm.nih.gov/pubmed/18347329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800979105
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