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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Activation of AMP-activated kinase (AMPK) in skeletal muscle increases glucose uptake, fatty acid oxidation, and mitochondrial biogenesis by increasing gene expression in these pathways. However, the transcriptional components that are directly targeted by AMPK are still elusive. The peroxisome-prol...

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Bibliografske podrobnosti
Main Authors: Jäger, Sibylle, Handschin, Christoph, St.-Pierre, Julie, Spiegelman, Bruce M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924552/
https://ncbi.nlm.nih.gov/pubmed/17609368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705070104
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