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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Activation of AMP-activated kinase (AMPK) in skeletal muscle increases glucose uptake, fatty acid oxidation, and mitochondrial biogenesis by increasing gene expression in these pathways. However, the transcriptional components that are directly targeted by AMPK are still elusive. The peroxisome-prol...

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Detalles Bibliográficos
Main Authors: Jäger, Sibylle, Handschin, Christoph, St.-Pierre, Julie, Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924552/
https://ncbi.nlm.nih.gov/pubmed/17609368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705070104
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