A fundamental system of cellular energy homeostasis regulated by PGC-1α

Maintenance of ATP levels is a critical feature of all cells. Mitochondria are responsible for most ATP synthesis in eukaryotes. We show here that mammalian cells respond to a partial chemical uncoupling of mitochondrial oxidative phosphorylation with a decrease in ATP levels, which recovers over se...

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Detalhes bibliográficos
Main Authors: Rohas, Lindsay M., St-Pierre, Julie, Uldry, Marc, Jäger, Sibylle, Handschin, Christoph, Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876550/
https://ncbi.nlm.nih.gov/pubmed/17470778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702683104
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