The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle

Peripheral arterial disease (PAD) affects 5 million people in the US and is the primary cause of limb amputations. Exercise remains the single best intervention for PAD, in part thought to be mediated by increases in capillary density. How exercise triggers angiogenesis is not known. PPARγ coactivat...

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Hauptverfasser: Chinsomboon, Jessica, Ruas, Jorge, Gupta, Rana K., Thom, Robyn, Shoag, Jonathan, Rowe, Glenn C., Sawada, Naoki, Raghuram, Srilatha, Arany, Zoltan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795492/
https://ncbi.nlm.nih.gov/pubmed/19966219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909131106
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