The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle

Peripheral arterial disease (PAD) affects 5 million people in the US and is the primary cause of limb amputations. Exercise remains the single best intervention for PAD, in part thought to be mediated by increases in capillary density. How exercise triggers angiogenesis is not known. PPARγ coactivat...

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Detalhes bibliográficos
Main Authors: Chinsomboon, Jessica, Ruas, Jorge, Gupta, Rana K., Thom, Robyn, Shoag, Jonathan, Rowe, Glenn C., Sawada, Naoki, Raghuram, Srilatha, Arany, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795492/
https://ncbi.nlm.nih.gov/pubmed/19966219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909131106
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