Hypoxic Induction of Vascular Endothelial Growth Factor (VEGF) and Angiogenesis in Muscle by Truncated Peroxisome Proliferator-activated Receptor γ Coactivator (PGC)-1α

The transcriptional coactivator peroxisome proliferator-activator receptor γ coactivator (PGC)-1α is required for full hypoxic induction of vascular endothelial growth factor (VEGF) in skeletal muscle cells. Under normoxic conditions, PGC-1α also strongly induces mitochondrial biogenesis, but PGC-1α...

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Detalles Bibliográficos
Main Authors: Thom, Robyn, Rowe, Glenn C., Jang, Cholsoon, Safdar, Adeel, Arany, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979394/
https://ncbi.nlm.nih.gov/pubmed/24505137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554394
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