Separation of the gluconeogenic and mitochondrial functions of PGC-1α through S6 kinase

PGC-1α is a transcriptional coactivator that powerfully regulates many pathways linked to energy homeostasis. Specifically, PGC-1α controls mitochondrial biogenesis in most tissues but also initiates important tissue-specific functions, including fiber type switching in skeletal muscle and gluconeog...

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Detalhes bibliográficos
Main Authors: Lustig, Yaniv, Ruas, Jorge L., Estall, Jennifer L., Lo, James C., Devarakonda, Srikripa, Laznik, Dina, Choi, Jang Hyun, Ono, Hiraku, Olsen, Jesper V., Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127426/
https://ncbi.nlm.nih.gov/pubmed/21646374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2054711
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