Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation

Heparan sulfate (HS) proteoglycans influence embryonic development and adult physiology through interactions with protein ligands. The interactions depend on HS structure, which is determined largely during biosynthesis by Golgi enzymes. How biosynthesis is regulated is more or less unknown. During...

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Bibliografiska uppgifter
Huvudupphovsmän: Presto, Jenny, Thuveson, Maria, Carlsson, Pernilla, Busse, Marta, Wilén, Maria, Eriksson, Inger, Kusche-Gullberg, Marion, Kjellén, Lena
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2008
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290785/
https://ncbi.nlm.nih.gov/pubmed/18337501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705807105
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