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The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis

The d-glucuronyltransferase and N-acetyl-d-glucosaminyltransferase reactions in heparan sulfate biosynthesis have been associated with two genes, EXT1 and EXT2, which are also implicated in the inherited bone disorder, multiple exostoses. Since the cell systems used to express recombinant EXT protei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Senay, Claire, Lind, Thomas, Muguruma, Kumi, Tone, Yuko, Kitagawa, Hiroshi, Sugahara, Kazuyuki, Lidholt, Kerstin, Lindahl, Ulf, Kusche-Gullberg, Marion
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083719/
https://ncbi.nlm.nih.gov/pubmed/11256613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd045
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