The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis

The d-glucuronyltransferase and N-acetyl-d-glucosaminyltransferase reactions in heparan sulfate biosynthesis have been associated with two genes, EXT1 and EXT2, which are also implicated in the inherited bone disorder, multiple exostoses. Since the cell systems used to express recombinant EXT protei...

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Bibliografiska uppgifter
Huvudupphovsmän: Senay, Claire, Lind, Thomas, Muguruma, Kumi, Tone, Yuko, Kitagawa, Hiroshi, Sugahara, Kazuyuki, Lidholt, Kerstin, Lindahl, Ulf, Kusche-Gullberg, Marion
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2000
Ämnen:
Scientific Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083719/
https://ncbi.nlm.nih.gov/pubmed/11256613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd045
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