The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis

The d-glucuronyltransferase and N-acetyl-d-glucosaminyltransferase reactions in heparan sulfate biosynthesis have been associated with two genes, EXT1 and EXT2, which are also implicated in the inherited bone disorder, multiple exostoses. Since the cell systems used to express recombinant EXT protei...

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Detalhes bibliográficos
Main Authors: Senay, Claire, Lind, Thomas, Muguruma, Kumi, Tone, Yuko, Kitagawa, Hiroshi, Sugahara, Kazuyuki, Lidholt, Kerstin, Lindahl, Ulf, Kusche-Gullberg, Marion
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083719/
https://ncbi.nlm.nih.gov/pubmed/11256613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd045
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