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Intrasteric control of AMPK via the γ(1) subunit AMP allosteric regulatory site
AMP-activated protein kinase (AMPK) is a αβγ heterotrimer that is activated in response to both hormones and intracellular metabolic stress signals. AMPK is regulated by phosphorylation on the α subunit and by AMP allosteric control previously thought to be mediated by both α and γ subunits. Here we...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2286513/ https://ncbi.nlm.nih.gov/pubmed/14691231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03340004 |
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