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Post-translational modifications of the beta-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization.

The AMP-activated protein kinase (AMPK) is a ubiquitous mammalian protein kinase important in the adaptation of cells to metabolic stress. The enzyme is a heterotrimer, consisting of a catalytic alpha subunit and regulatory beta and gamma subunits, each of which is a member of a larger isoform famil...

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Main Authors: Warden, S M, Richardson, C, O'Donnell, J, Stapleton, D, Kemp, B E, Witters, L A
格式: Artigo
語言:Inglês
出版: 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221653/
https://ncbi.nlm.nih.gov/pubmed/11171104
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