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The Alpha Subunit of Nitrile Hydratase Is Sufficient for Catalytic Activity and Post-Translational Modification

[Image: see text] Nitrile hydratases (NHases) possess a mononuclear iron or cobalt cofactor whose coordination environment includes rare post-translationally oxidized cysteine sulfenic and sulfinic acid ligands. This cofactor is located in the α-subunit at the interfacial active site of the heterodi...

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Bibliographische Detailangaben
Hauptverfasser: Nelp, Micah T., Astashkin, Andrei V., Breci, Linda A., McCarty, Reid M., Bandarian, Vahe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075990/
https://ncbi.nlm.nih.gov/pubmed/24914472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500260j
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