The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

VHL, NF-1, c-Ret, and Succinate Dehydrogenase Subunits B and D act on a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells and requires the EglN3 prolyl hydroxylase as a downstream effector. Germline mutations of these gene...

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Detalhes bibliográficos
Main Authors: Schlisio, Susanne, Kenchappa, Rajappa S., Vredeveld, Liesbeth C.W., George, Rani E., Stewart, Rodney, Greulich, Heidi, Shahriari, Kristina, Nguyen, Nguyen V., Pigny, Pascal, Dahia, Patricia L., Pomeroy, Scott L., Maris, John M., Look, A. Thomas, Meyerson, Matthew, Peeper, Daniel S., Carter, Bruce D., Kaelin, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279200/
https://ncbi.nlm.nih.gov/pubmed/18334619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1648608
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