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EglN2 positively regulates mitochondrial function in breast cancer

Oxygen sensing is associated with mitochondrial function. EglN2, which contributes to breast tumorigenesis as a prolyl hydroxylase, has recently been identified as a transcription co-activator through interaction with NRF1 and PGC1α to regulate mitochondrial function under conditions of normoxia and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Zhang, Jing, Zheng, Xingnan, Zhang, Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905419/
https://ncbi.nlm.nih.gov/pubmed/27308620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1120845
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