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Leishmania-released nucleoside diphosphate kinase prevents ATP-mediated cytolysis of macrophages

Leishmania amazonensis was found to release nucleoside diphosphate kinase (NdK) - a stable enzyme capable of decreasing extracellular ATP. The release of this enzyme from Leishmania results in its progressive accumulation extracellularly as they replicate, peaking at the stationary phase in vitro. T...

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Detalhes bibliográficos
Main Authors: Kolli, Bala Krishna, Kostal, Jan, Zaborina, Olga, Chakrabarty, Ananda M., Chang, Kwang-Poo
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277215/
https://ncbi.nlm.nih.gov/pubmed/18242727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2007.12.010
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