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Crystal structure and biophysical characterization of the nucleoside diphosphate kinase from Leishmania braziliensis
BACKGROUND: Nucleoside diphosphate kinase (NDK) is a housekeeping enzyme that plays key roles in nucleotide recycling and homeostasis in trypanosomatids. It is also secreted by the intracellular parasite Leishmania to modulate the host response. These functions make NDK an attractive target for drug...
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| Publicado en: | BMC Struct Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4322457/ https://ncbi.nlm.nih.gov/pubmed/25643978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-015-0030-8 |
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