Crystal structure and biophysical characterization of the nucleoside diphosphate kinase from Leishmania braziliensis

BACKGROUND: Nucleoside diphosphate kinase (NDK) is a housekeeping enzyme that plays key roles in nucleotide recycling and homeostasis in trypanosomatids. It is also secreted by the intracellular parasite Leishmania to modulate the host response. These functions make NDK an attractive target for drug...

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Detalhes bibliográficos
Publicado no:BMC Struct Biol
Main Authors: Vieira, Plínio Salmazo, de Giuseppe, Priscila Oliveira, Murakami, Mario Tyago, de Oliveira, Arthur Henrique Cavalcante
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322457/
https://ncbi.nlm.nih.gov/pubmed/25643978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-015-0030-8
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