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Photodynamic inactivation of Leishmania braziliensis doubly sensitized with uroporphyrin and diamino-phthalocyanine activates effector functions of macrophages in vitro

Photodynamic inactivation of Leishmania has been shown to render them non-viable, but retain their immunological activities. Installation of dual photodynamic mechanisms ensures complete inactivation of species in the Leishmania subgenus, raising the prospect of their safe and effective application...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sharma, Rohit, Viana, Sayonara M., Ng, Dennis K. P., Kolli, Bala K., Chang, Kwang Poo, de Oliveira, Camila I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555832/
https://ncbi.nlm.nih.gov/pubmed/33051524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74154-1
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