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Episomal Expression of Specific Sense and Antisense mRNAs in Leishmania amazonensis: Modulation of gp63 Level in Promastigotes and Their Infection of Macrophages In Vitro

The major surface glycoprotein (gp63) of Leishmania amazonensis is a metalloprotease implicated in the infection of mammalian macrophages. The expression of gp63 and its participation in this infection were further examined by modulating the level of this molecule in a virulent gp63-abundant wild-ty...

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Detalhes bibliográficos
Main Authors: Chen, De-Qiao, Kolli, Bala Krishna, Yadava, Nagendra, Lu, Hong Gang, Gilman-Sachs, Alice, Peterson, Daniel A., Chang, Kwang-Poo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97104/
https://ncbi.nlm.nih.gov/pubmed/10603371
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