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Mutation of Y(179) on phospholipase D2 (PLD2) upregulates DNA synthesis in a PI3K- and Akt-dependent manner

Phospholipase D2 (PLD2), one of the two mammalian members of the PLD family, has been implicated in cell proliferation, transformation, tumor progression and survival. However, as precise mechanistic details are still unknown, we investigated here if the PLD2 isoform would signal through the PI3K/AK...

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Bibliografske podrobnosti
Main Authors: Di Fulvio, Mauricio, Frondorf, Kathleen, Gomez-Cambronero, Julian
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276604/
https://ncbi.nlm.nih.gov/pubmed/18006275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.10.009
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